CHEM 165. 3-D Cryo-Electron Microscopy of Macromolecules and Cells (4 units)
Link to catalog page: https://catalog.ucsd.edu/courses/CHEM.html#chem165
Description
The resolution revolution in cryo-electron microscopy has made this a key technology for the high-resolution determination of structures of macromolecular complexes, organelles, and cells. The basic principles of transmission electron microscopy, modern cryo-electron microscopy, image acquisition, and 3-D reconstruction will be discussed. Examples from the research literature using this state-of-the-art technology will also be discussed. Prerequisites: CHEM 114A or BIBC 100.
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Successor courses
No courses have CHEM 165 as a prerequisite.